Cluster of Excellence “Controlling Microbes to Fight Infections” (CMFI)

The surfaces of the human body host colonies of microorganisms, known as microbiomes. Along with bacteria which have a positive effect on human health, microbiomes contain potentially life-threatening pathogens. In the past, broad-spectrum antibiotics have often been used to tackle them. Nowadays it is known that this not only promotes resistance to antibiotics – in many cases, it also damages the microbiome as a whole.

CMFI researchers aim to develop new strategies to control microbial mechanisms and fight infections.

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The Cluster of Excellence CMFI brings together researchers from different disciplines such as infection biology, immunology, bioinformatics, pharmaceutical biology, antibiotics research, molecular and medical microbiology, biotechnology, environmental biology, systems biology, chemistry, and medical history and ethics. Their common goal is to elucidate the mechanisms of interaction between beneficial and harmful bacteria and the host in order to develop novel targeted therapeutic and anti-infective treatments.

The CMFI is one of more than 50 Clusters of Excellence funded by German federal and state governments as part of the Excellence Strategy to sustainably strengthen Germany as a center of science, improve its international competitiveness and make cutting-edge research at German universities visible. In addition to the University of Tübingen, the Max Planck Institute for Biology and the University Hospital Tübingen are involved in the CMFI.

Biomedical Science Research Center “Alexander Fleming” (BSRC FLEMING)

The Biomedical Science Research Center “Alexander Fleming” (BSRC FLEMING) was established through the efforts of Amalia Koutsouri-Fleming, a microbiologist and wife of Alexander Fleming, the Nobel Laureate 1945 in Medicine. She had the vision for a Greek Center of Scientific and Technological Excellence, based on meritocracy, excellence and innovation purposed to attract and develop young Greek researchers.
BSRC FLEMING started its operation in 1999 and is nowadays a top-ranked non-profit research organization of 23 group leaders and 130 researchers, with a mission to perform cutting edge basic and translational research in biomedical sciences, provide state-of the-art training and mentorship to scientists and students of all levels, offer high end scientific and technological services, and engage in technology transfer and innovation. The center is located in an area of 128.000 sq.m. in Vari, a region on the Athenian Riviera. The Fleming Museum of Contemporary Science is also housed on the premises of the research center.

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Its main research directions include Immunity & Inflammation, Neuroscience, Cancer Biology, RNA Biology & Epigenetics, Bioinformatics & Computational Biology. Additionally, BSRC FLEMING has recently established its frontier research in Biomolecular Engineering & Synthetic Biology with a European Research Area chair (ERA Chair), Dr. Georgios Skretas. These research directions reflect the work of its group leaders and serve as links between the two FLEMING Institutes: Institute for Bioinnovation (IBI) and Institute for Fundamental Biomedical Research (IFBR). The focus of IFBR is on unravelling the molecular and cellular basis of disease via novel animal models of human pathologies, while IBI’s vision is to advance fundamental research achievements towards innovative translational biotechnologies and drug development.
BSRC FLEMING’s strength and international recognition arises from pioneering research towards understanding the molecular and cellular basis of human diseases, and development and validation of relevant animal models of chronic inflammatory diseases, neurodegenerative disorders, metabolic diseases, cancer and autoimmune syndromes, among others, and the development of new approaches for their diagnosis and treatment, using transdisciplinary approaches and state-of the art facilities and technologies. It is of note that several of its researchers have been included in the list of outstanding research leaders in Europe awarded ERC grants.
The center also coordinates two major Research Infrastructures (RIs) for modeling human diseases and bioinformatics/biocomputing resources, while it participates in personalized medicine, precision oncology and bioimaging RIs.


August Pi i Sunyer Biomedical Research Institute (IDIBAPS)

IDIBAPS is one of the leading biomedical research centers in Spain with an international projection. IDIBAPS is uniquely located in the Campus Clínic in Barcelona, joining efforts with the Faculty of Medicine of the University of Barcelona and the Hospital Clínic of Barcelona to carry out excellent biomedical research and investigate the most common diseases in our society. Our mission is translational research; that is, we look to ensure that the questions that arise at the patient’s bedside find answers in the laboratory and that advances made in the laboratory are translated rapidly to the patient.

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IDIBAPS research is organized into research areas and multidisciplinary programs.

5 Research Areas and 3 transversal groups:
1. Biological aggression and response mechanisms
2. Respiratory, cardiovascular and renal pathobiology and bioengineering
3. Liver, digestive system and metabolism
4. Clinical and experimental neuroscience
5. Oncology and haematology
6. Transversal research groups focusing on primary care, pharmacology and nursing

Multidisciplinary Programs:
1. Transitional cancer research program
2. Lymphoid neoplasms program
3. Synaptic autoimmunity in neurology, psychiatry and cognitive neuroscience program

Among the multiple research groups, we would like to highlight the following research lines, supported by ERC grants, for the FRONTIERS Science Journalism Residency Program:
– Neuronal control of metabolism directed by Marc Claret, Principal Investigator of MITOSENSING project: https://cordis.europa.eu/project/id/725004
– Cortical circuit dynamics directed by Jaime de la Rocha, Principal Investigator of PRIORS project: https://cordis.europa.eu/project/id/683209
– Molecular pathology of lymphoid neoplasms directed by Elías Campo, Principal Investigator of BCLLatlas project: https://cordis.europa.eu/project/id/810287

Center for Neuroscience and Cell Biology & Centre for Innovative Biomedicine and Biotechnology

CiBB – Centre for Innovative Biomedicine and Biotechnology, is a Research Center of excellence in the domains of Biomedicine and Biotechnology, which results from a consortium joining CNC-UC — Center for Neuroscience and Cell Biology and iCBR – Coimbra Institute for Clinical and Biomedical Research. In 2024, the Teaming projects MIA-Portugal: Multidisciplinary Institute of Ageing and GeneT – Gene Therapy Center of Excellence have integrated the CiBB multidisciplinary structure.

We can offer an exciting opportunity to delve into the dynamic world of biomedical research and science communication. This fellowship provides hands-on experience in communicating biomedical discoveries through various mediums, including media interactions, video production, and social media management. The FRONTIERS fellows will have the chance to collaborate with an experienced and passionate team, learning and contributing to effective strategies in scientific communication.
The fellowship allows for direct interaction with top researchers in four distinct areas of biomedicine, providing a comprehensive insight into the latest findings and trends in biomedical research.

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Furthermore, the work environment fosters a strong culture of science communication, offering fellows a full immersion into the realm of scientific outreach. Fellows will have the opportunity to develop essential communication skills, create engaging content, and broaden the reach of scientific discoveries to the general public. This fellowship is ideal for professionals interested in exploring the intersection of science, journalism, and digital communication while collaborating with a multidisciplinary and inspiring team.

This offers an immersive experience within the vibrant ecosystem of CNC-UC / CiBB, providing fellows with unique access to the forefront of biomedical research and science communication. Fellows will be fully integrated into the CNC-UC / CiBB community and will have the opportunity to attend weekly scientific seminars and thematic retreats, gaining invaluable insights into cutting-edge research across various biomedical disciplines. They will actively participate in the institution’s science communication dynamics, engaging in various outreach activities and gaining access to scientific platforms to observe experiments and scientific endeavors firsthand.

More about CiBB
With the largest critical mass of researchers in the Centre Region of Portugal, internationally recognized and linked to the Faculties of Pharmacy, Medicine, Sciences and Technology and Economics, as well as to the Institute of Interdisciplinary Research and to the Coimbra University Hospital, CiBB has a high-level of scientific production and attracts talent and funding at national and international levels.

The CiBB stands as the flagship of Biomedical and Biotechnology Sciences at the University of Coimbra (UC). It is the largest R&D Unit in the center region of Portugal and the sole UC-coordinated Associate Laboratory (top 100% evaluation), welcoming circa 700 members.
CiBB comprises 37 dynamic and multidisciplinary research groups, dedicated to understanding how and why diseases develop, particularly those associated with aging, and translating this understanding into clinical applications and technological breakthroughs.
Structured around four thematic pillars, CIBB’s mission spans diverse areas:
1. Neuroscience and Disease: Delving into brain function and dysfunction in disorders such as neurodegenerative diseases, neuropsychiatric conditions, and vision impairments.
2. Metabolism, Aging, and Disease: Investigating the cellular and molecular underpinnings of metabolic dysfunction and aging, and their impact on age-related diseases.
3. Innovative Therapies: Harnessing the potential of stem cells, genetic interventions, and pharmaceuticals to pioneer new treatments for neurodegenerative, cardiovascular, oncological, and infectious conditions.
4. Healthcare Challenges: Tackling healthcare challenges by promoting evidence-based decision-making, engaging citizens, and finding innovative solutions for aging-related questions.
CiBB is committed to nurturing talent, through robust international training programs at the master’s and doctoral levels. Additionally, CiBB bridges the gap between research and society through effective communication and public engagement initiatives.
In collaboration with the Coimbra University Hospital and its Clinical Academic Center, CiBB leverages its strong ties to clinical practice, facilitating the translation of fundamental research findings into clinical benefits. Moreover, CiBB invests on the transformation of scientific breakthroughs into intellectual property, fostering technology transfer and the creation of economic value.

Note: We are open to developing projects that encompass a broader scope, involving communication across different areas of the center, and/or focusing on specific ongoing research projects within the center.


Leibniz Institute for Natural Product Research and Infection Biology

We dedicate our research to natural products from micro-organisms and the infection biology of pathogenic fungi. Microbial natural products serving as mediators in the biological communication are essential for our lives. However, they play an ambivalent role in this process: On the one hand, they are involved in the emergence of numerous infectious diseases; on the other hand, they belong to the most important sources of medicinal products like antibiotics.

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In order to examine microbial natural products and to understand infectious diseases better, we combine both areas of research. We aim to elucidate how microorganisms produce both pathogenic substances and pharmacologically relevant components. Beyond that, these substances of micro-organisms serve as instruments of communication among themselves. Another module of our research is the interaction of pathogenic microorganisms with their host. We are interested in investigating the methods and tricks that both parties use in this process.

Numerous individual joint projects enable us to acquire new knowledge in the field of biosynthesis and the function of natural products. We use this knowledge to develop innovative ingredients for the diagnosis and therapy of illnesses, including new anti-infectives. Implementing our research results and the models derived thereof, we contribute to the development of a systems biology of infections.

Leibniz Institute for Prevention Research and Epidemiology – BIPS

The Leibniz Institute for Prevention Research and Epidemiology – BIPS develops effective strategies for the prevention of chronic, non-communicable diseases. Supporting a healthy life-course early on is our primary goal. The focus of our research is therefore on factors beyond individual diseases, such as lifestyle and environment, biological and social factors, as well as early detection and drug safety. Our research spectrum covers methodological development, the identification of the causes of diseases, and intervention and implementation research. We also offer information to politicians and the general population and provide academic qualification to young scientists. BIPS thus covers the entire cycle of epidemiological research.

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Under the central theme of “population-based prevention research in the life-course,” the institute conducts interdisciplinary epidemiological health research on the national and international level. It develops innovative methods and utilizes diverse data sources to study significant health disorders and to evaluate preventive measures and strategies. In addition, BIPS significantly contributes to the establishment of research infrastructures of national and international importance. To this end, BIPS is also committed to the expansion of research data management and the FAIRification of research data as an important basis of Open Science and Open Data.

For many years, strengthening prevention has been a key scientific, social, and political objective. BIPS is dedicated to achieve this goal with high-quality research based upon methodological research investigating epidemiological questions with a focus on the development of epidemiological and statistical methods. The institute emphasizes the particular importance of the life-course perspective for the health of individuals and the population as a whole with its focus on long-term studies. Research at the institute provides important insights to ensure and improve health and well-being with measures that begin early and are related to transition periods within the life-course.

Leibniz Institute for Immunotherapy (LIT)

The Leibniz Institute for Immunotherapy (LIT) develops innovative therapies for the treatment of cancer, autoimmunity, and chronic inflammation. By reprogramming immune cells through synthetic and pharmacologic intervention, we build cells that save lives.

Our scientific activities are structured into three Research Areas: Discovery, Translation, and Clinical Application. All three work in synergy with one another. Our work starts with basic research into the areas of immune regulation, immune metabolism, cancer, and tissue homeostasis. It carries on with a focus on therapy development—spanning the creation of new formats of genetic and pharmacologic cell manipulation and drug-compliant manufacturing processes. Finally, we seek to apply our discoveries in early clinical trials on patients themselves.

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Discovery: This branch of research investigates the highly complex interactions of different immune cells—with each other and with the organism’s cells—to understand how the immune system maintains the health of the organism.
Translation: This area focuses specifically on the preclinical development of immune-cell therapeutics. This includes the identification, differentiation, expansion, and preclinical testing of therapeutically relevant immune cell populations.
Clinical Application: At the LIT, our core focus is on the clinical translation of scientific findings: We therefore place significant emphasis on the development and roll out of clinical trials and focus on the clinical implementation of the results.


Reinforcing under-utilised crops at the Portuguese living lab GPeaPort – The DIVINFOOD project

In Europe, an increasing number of consumers are embracing plant-based diets and reducing meat consumption. A 2021 survey found that around 30% of Europeans follow a flexitarian diet, focused on plant-base foods with occasional meat consumption. This dietary trend underscores the demand for improved, minimally processed, and nutrient-rich alternatives.
The DIVINFOOD project aims to develop food chains that value under-utilised agrobiodiversity, in order to act against the decline of biodiversity and meet the growing expectations of consumers for healthy, local products that contribute to sustainable food systems. DIVINFOOD operates holistically across the food chain, fostering collaboration among researchers, farmers, processors, market intermediaries, and consumers, to maximize cereals and legumes food chains, realizing their potential for diversified and healthy diets.

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Funded under the European Commission Horizon 2020 Sustainable Food Security call, DIVINFOOD boasts a consortium of 25 European institutions led by the Institut national de recherche pour l’agriculture, l’alimentation et l’environnement, in France, with four Portuguese partners: ITQB NOVA, Évora University, ADECA and Cooking lab. In Portugal, the project focuses on grass pea (Lathyrus sativus).
Carlota Vaz Patto coordinates the ITQB NOVA team engaged in DIVINFOOD, specifically the PlantX Lab. With a history of participatory research with local grass pea farmers in Alvaiázere, Portugal, the team has expanded its scope under DIVINFOOD to include a wider range of farmers and processors, establishing the Portuguese living lab, GPeaPort, under her coordination. Living labs are user-centric innovation systems that foster co-creation, integrating research and innovation within community contexts. GPeaPort aims to revitalize and value grass pea cultivation and use by enhancing varietal diversity and developing innovative food products with local food producers, consumers, chefs, cooks, small-scale processors, rural development associations, local authorities and researchers, using a citizen science approach.
At ITQB NOVA, the Genetics and Genomics of Plant Complex Traits (PlantX) Laboratory, led by Carlota Vaz Patto, specializes in molecular quantitative genetics applied to plant breeding. The lab focuses on identifying genes controlling complex interesting traits, such as disease/drought resistance or seed quality, to develop control models, scientific methods and molecular tools to assist precision breeding programs. Within the scope of DIVINFOOD, PlantX hopes to contribute to the diversification of grass pea production systems, through the improvement of its traditional varieties – boosting tolerance to drought, enhancing nutritional quality, and increasing production capacity. They hope to contribute, in collaboration with other Portuguese stakeholders, to diversify diets, by facilitating the implementation of alternative mild processing methods to obtain innovative food products.

State Museum of Natural History Stuttgart

The aim of SMNS research is to comprehensively understand changes in biodiversity at all levels – from genetic diversity to the diversity of species and communities to the level of ecosystems – over geological timescales. SMNS investigates how the diversity of organisms, species communities and interactions has developed in the course of evolution, discerning patterns of change over time and which biotic and abiotic environmental drivers are responsible for this. The SMNS investigates both evolutionary and anthropogenic influences on biodiversity across different temporal and spatial scales.

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Our expertise encompasses a wide variety of organisms, from charismatic Indonesian tarsiers under threat of extinction to thermophilic neophytes that have spread rapidly and conquered new habitats in the past decades in response to rising temperatures. From giant fossil marine reptiles that were dreaded top predators of the Jurassic Sea to millimeter-sized parasitoid wasps that lay their eggs in other insect larvae, preventing agricultural pests. With more than 12 million specimens in our collection and cutting-edge facilities, we investigate this diversity to unravel the uniqueness of each specimen. It is the fascinating stories behind each specimen that we convey not only in scientific articles but also to our visitors in the exhibition. Be it the first evidence of cancer from 240 million years ago, the predation among giant marine reptiles, as evidenced by bite marks or how the evolution of mouthparts contributed to the diversity we see in some hyperdiverse insect groups.
Through close collaborations, such as with the particle accelerator at KIT, we are able to use synchrotron radiation to create three-dimensional models of insects trapped in amber millions of years ago or visualize the behavior of live parasitoid wasps moving in their host.
We regularly carry out expeditions and paleontological excavations. Both in the vicinity, where many world-famous fossil deposits are easily accessible and also worldwide, with many highly important findings. They range from small, such as the oldest fossil hummingbird to the probably heaviest animal that ever lived on earth: Perucetus colossus. Our scientists describe new species from the meadows and forests in the area where most people would not expect to find the unknown. But also from remote areas such as cave systems across Europe, tropical rainforests or the islands of New Caledonia. We do this together with institutions and researchers from the area and maintain close collaborations that allow for capacity building and vice versa knowledge exchange on an eye level. We are active members in several networks, through which we are able to join forces with other natural history museums, universities and research institutions of all kinds to conduct large-scale projects, such as the German Barcode of Life.

Leibniz Institute for Zoo and Wildlife Research (IZW)

The IZW conducts wildlife research for conservation from a multidisciplinary perspective. We aim to understand key species’ evolutionary equipment, genetics, reproduction capacity, health and interaction with humans in the context of biodiversity loss and develop effective strategies for these species to cope with the massive and rapid environmental change of our time. We focus on wildlife biology and veterinary science, but also include data modelling, biostatistics, social sciences and other disciplines into our holistic approach for evidence-based species conservation. We conduct fundamental and applied research – from the molecular to the landscape level – in close dialogue with the public and stakeholders. Additionally, we are committed to unique and high-quality services for the scientific community.