Gulbenkian Institute for Molecular Medicine

The Gulbenkian Institute for Molecular Medicine (GIMM) was established in 2023 through the merger of the Instituto de Medicina Molecular João Lobo Antunes (iMM) and Instituto Gulbenkian de Ciência (IGC), two leading research institutes in Portugal. GIMM is dedicated to pioneering frontier research that pushes the boundaries of scientific knowledge and addresses pressing global health challenges. Its vision is grounded in a commitment to scientific excellence and societal impact, making it a hub for groundbreaking discoveries that transform our understanding of biology and human health.
GIMM’s 39 research groups, comprising over 700 researchers, are dedicated to six core scientific areas: cell and developmental biology, gene regulation, evolution, host-pathogen interactions, immunity and inflammation, and neurosciences. By exploring these fields, GIMM aims to answer fundamental questions that drive the development of innovative solutions, from basic scientific discoveries to tangible healthcare applications. Its work not only advances the frontiers of molecular medicine but also seeks to bridge the gap between discovery and practical application, ensuring that its findings directly contribute to improving health outcomes and promoting equity on a global scale.

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In fact, GIMM’s structure includes two core components: GIMM Discovery, which focuses on fundamental research and the pursuit of scientific breakthroughs, and GIMM Care, which emphasizes the application of scientific knowledge to improve healthcare and quality of life. Through the Care initiative, GIMM aims to revolutionize clinical and translational research by creating a pioneering Center of Excellence in Portugal. This people-centered, data-driven model brings together a diverse range of stakeholders to collaboratively address key health challenges, accelerate the translation of research into clinical practice, and foster innovative solutions that respond to the most urgent healthcare needs.

Through these efforts, GIMM stands at the forefront of global efforts to enhance scientific understanding and improve human health, making it an ideal partner for those committed to supporting cutting-edge research with profound societal impact.

Frontier Research

At GIMM, we position our science at the forefront of frontier research by embracing a bold and transformative approach to discovery that integrates fundamental and applied research. Our unique structure, divided into GIMM Discovery and GIMM Care, embodies this vision by unifying curiosity-driven exploration with a focus on real-world healthcare solutions.
GIMM Discovery is the heart of our fundamental research, where scientists are encouraged to pursue groundbreaking ideas that push the boundaries of our understanding of biology and human health. This component thrives on curiosity-driven research, fostering a culture where curiosity, innovative thinking and interdisciplinary collaboration are encouraged. By nurturing this exploratory spirit, GIMM Discovery not only advances our knowledge but also lays the groundwork for future innovations that can have profound impacts on science and society.
GIMM Care, on the other hand, is dedicated to translating these fundamental discoveries into practical applications that directly address healthcare challenges. By focusing on clinical and translational research, GIMM Care aims to shorten the path from fundamental scientific discoveries to real-world health solutions. This component brings together a diverse network of stakeholders, including clinicians, researchers, patients, and industry partners, to co-create innovative, data-driven approaches that enhance health outcomes and promote equity.
The synergy between GIMM Discovery and GIMM CARE ensures a dynamic flow of knowledge and innovation, where fundamental research informs applied projects, and practical needs inspire new scientific questions. This interconnected approach enables GIMM to rapidly adapt to evolving healthcare challenges, driving both scientific excellence and societal impact. By bridging the divide between curiosity-driven research and its application, we position GIMM not just as a leader in molecular medicine but as a catalyst for transformative change in global health.
Beyond the walls of GIMM, we actively shape the national and European R&D landscape through collaboration, promoting excellence in research and training, and engaging society in scientific and cultural development. Our efforts extend beyond traditional boundaries, pushing the limits of scientific knowledge and making a profound impact on global health and well-being. By focusing on ensuring these values and aims, GIMM stands at the forefront of frontier research, driving transformative change and advancing the frontiers of molecular medicine.


Babeș-Bolyai University Cluj-Napoca

Babeș-Bolyai University in Cluj-Napoca (BBU) is one of Romania’s most prestigious and dynamic universities, committed to academic excellence, innovation, and community impact. Its main strength is the comprehensive approach to research, from natural sciences and engineering to cognitive sciences and humanities. Located in a growing tech-hub, BBU is involved in identifying solutions to the environmental and human challenges brought by economic growth, and in preserving local heritage through frontier research.

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PROGRESS: Reading provenance from ubiquitous quartz: understanding the changes occurring in its lattice defects in its journey in time and space by physical methods .
ERC-funded project developing a new, beyond state of the art, provenance and multi-scale time analysis method for rock samples, based on analyzing quartz – an abundant mineral, whose structure and defects can record time as they trap charge during interaction with natural radioactivity.

Institute of Interdisciplinary Research in Bio-Nano-Sciences.
The main BBU facility for experimental interdisciplinary research, with a focus on bio-, nano-sciences, and on the interface of biosystems with artificially or naturally nanostructured systems. Transferring the experimental results into industry is also one of the institute’s main goals.

Strengthening the Research Capacities for Extreme Weather Events in Romania – SCEWERO.
Horizon-funded project aiming at developing AI-enhanced abilities to forecast extreme heat and precipitation events using emerging technologies. The goal is to redesign the thresholds for early warnings in Romania for heat events, currently undervalued, and to increase the communities’ resilience when facing such extreme events.

The PsyTech-MATRIX PLATFORM – Platform for Robotics/Robotherapy and Virtual Reality Enhanced Therapy.
Platform hosting laboratories and technologies underlying the integration of psychology and technology as means of evidence-based mental health services. It focuses on stress control, enhanced cognitive-behavioral therapies for children, adolescents and parents, and makes use of digital affective technologies and therapeutic robots.

RESTORY – Recovering Past Stories for the Future: A Synergistic Approach to Textual and Oral Heritage of Small Communities.
Horizon-funded project focused on the challenges faced by small and middle-sized communities of past and present in sustainably managing and reusing a limited amount of human and material resources, with the aim of helping citizens and researchers understand the drives behind (re)use and (re)adaptations.

NOTA – Note-taking and Notebooks as Channels of Medieval Academic Dissemination across Europe.
ERC-funded project studying medieval university learning by delving into deep creative reflections on the motivation and technical aspects involved in producing notebooks of the 14th and 15th centuries, when paper entered universities, aiming to elucidate their role in knowledge transfer.

Cosmology & Astroparticle physics

Our group works on the fields of theoretical cosmology and astroparticle physics with the goal of understanding the fundamental laws of the universe, exploiting synergies between astrophysical observations and laboratory experiments. This project would be embedded within UNDARK, a recently founded consortium funded by the EU “Widening participation and spreading excellence programme” (TWINNING project number 101159929). This consortium will carry out, from 2024 until 2027 and in collaboration with other partner institutions such as CERN, or the CNRS, an intense scientific and outreach program focused on shedding light on the so-called “dark universe”.

As we currently know from astrophysical observations, barely 18% of the total matter of the Cosmos is made up of the elements in atoms with which we are familiar, while the remaining 82%, termed dark matter, is the dominant type of matter in galaxies. In addition, all matter, ordinary and dark, currently only makes up 31% of the energy in the universe, with the rest being an even more mysterious component called dark energy which causes the universe as a whole to accelerate while it is expanding.

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Advancing these fundamental questions is currently the focus of a multidisciplinary effort at the frontiers of astroparticle physics and cosmology, that is setting the scene for future scientific breakthroughs. Among these major puzzles, the problem of dark matter exhibits the most diverse set of observational manifestations, ranging from the cosmic microwave background and the large-scale distribution of galaxies to galactic dynamics. Hence, this area of astroparticle physics is the subject of extensive theoretical scrutiny.

The ultimate scientific goal of the UNDARK consortium is to explore the dark universe and, in particular, discover what is dark matter made of. For this, we plan to use the state-of-the-art telescopes and facilities installed in the Canary Islands Observatories with the assistance of world-class institutions on the fields of astroparticle physics and cosmology. We have planned a vibrant scientific and artistic exchange program, several scientific meetings and schools, as well as there will be scientific staff and a scientific illustrator hired under the project.

Chalmers University of Technology

Chalmers University of Technology in Gothenburg, Sweden, conducts research and education in technology and natural sciences at a high international level. The university has 3,100 employees and 10,000 students, and offers education in engineering, science, shipping and architecture.

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Some research areas to highlight:

Cutting edge quantum research
Chalmers is building Sweden’s first quantum computer and developing quantum algorithms for application in massive simulations in the research centre WACQT. Also being studied are new quantum materials for quantum technologies, quantum sensing and quantum optics.

Materials research for green transition
At Chalmers, there is experimental and theoretical research in the field of energy. This includes the conversion of solar energy and energy storage in novel batteries to large-scale transport of energy, with significant breakthroughs in structural batteries and floating solar energy. The research is conducted on renewable raw materials, lightweight materials and reduced environmental impact of materials.

Optimisation of human health
Chalmers has a field of research that focuses on optimisation of human health. This includes cutting edge research in the development of improved diagnostics, prevention of resistant bacterial infections, including through the development of materials such as graphene and gels, new methods for drug delivery and precision nutrition.

Microwave and antenna technology
At Chalmers, there are close collaborations with industry leaders for certain research, including improvement of hardware, such as transmitters and receivers for 6G, integration of gallium nitride technology and space components required to perform in extreme conditions. Researchers are developing the wireless systems of the future for everything from cancer treatment to self-driving cars, fast mobile networks and space antennas. Chalmers’ cleanroom and Gigahertz lab are world-class research environments.

Sustainable energy systems
At Chalmers, there is research on electric power generation and distribution to increase renewable and variable electricity in the power system, as well as research into materials and diagnostics for high-voltage networks. Within energy, road transport is the dominant field of research, but there are also studies looking into hydrogen, electric and hybrid vehicles, how a vehicle’s energy impacts design and environmental impact, as well as industrial combustion and gasification processes, carbon capture and energy systems analysis.

About the city of Gothenburg
Gothenburg is an open and welcoming city on the west coast, with a buzzing city centre, a picturesque archipelago and great travel connections to all the capital cities nearby. The city is leading the way in technology and logistics, being the hub for Northern Europe’s automotive industry and the main port for northern Europe. It also boasts thriving industry clusters and two highly ranking universities.


Genome of Europe

The Genome of Europe project is at the forefront of science and will -for the first time- bring together a large and comprehensive genetic dataset of DNA variation across all major groups of citizens living in Europe. GoE represents a unique collaboration across >30 countries to gather genetic information from their citizens as a reference database and make that accessible for medical and basic research. It is a very important first step to start using genetic information in health care and prevention, in particular in personalized or precision medicine and prevention.
So far, several genetic datasets have been available to scientists but these were relatively small and biased towards in particular inhabitants of the USA and UK. While the current GoE project is funded to collect at least 100,000 genomes of European citizens, the GoE database is expected to grow to >500,000 reference genomes as part of the 1 million genomes initiative (https://digital-strategy.ec.europa.eu/en/policies/1-million-genomes). The GoE project promotes scientific excellence by bringing together the major genetic groups, bio-informaticians, ELSI experts, and sequencing centers across Europe (>50 institutes and >200 scientists) which will collaborate in creating the GoE database for the coming 4 years.

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The project is highly innovative for genomics technology by using (combinations of) the latest whole genome sequencing techniques from diverse companies including Illumina, PacBio, Oxford Nanopore Technologies (ONT), and MGI. These include so-called long read sequencing techniques which have so far never been used in any genome database. Long read genome sequencing techniques allow to reveal the last missing 10% of the human genome after the Human Genome Project and its sequela since 2000 have determined the first 90% by short read technologies. GoE will boost such technological innovation and bring Europe to the forefront of genomics at the international stage.
Several ground breaking pilot projects are embedded that will use the genetic data as collected within GoE, such as the calibration of the polygenic risk scores (PRS) to local genetic variation. PRS are now widely investigated and also touted to move precision medicine and prevention forward, especially for the most common diseases of our greying society such as cancer, dementia, diabetes, osteoporosis and osteoarthritis, and cardiovascular diseases. The large and diverse GoE dataset will allow such PRS to be implemented across European population subgroups that differ in their genetic background. Examples include the application of PRS in breast cancer screening programs based on mammography, cardiovascular screening programs using genetically determined cholesterol levels, and use of pharmacogenetic information to select and optimize medication.

Department of Mathematics – University of Valencia

The research done in applied mathematics can be crucial to numerical simulations in other fields in physics and astrophysics, so the nature of my research is quite multidisciplinary since input from the field associated to the simulations is crucial to succeeding. On the other hand, the gravitational wave astronomy field is qualified as frontier research due to the complexity of the research in all the areas involved, from building of the detectors to modeling source and development of data analysis techniques. Understanding the universe and all their fascinating objects has always had a great impact in our society.

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The research lines focus on applied mathematics and astrophysics, with special interest in the development of numerical methods for partial differential equations, numerical relativity and gravitational waves. Isabel Cordero-Carrión is currently a member of the Virgo Collaboration as part of the Valencia Virgo group. In this role, she holds several management positions: Isabel serves as one of the two co-ombudspersons, is the current Virgo outreach coordinator, and is a member of the Core Program committee. Additionally, she is involved with the Einstein Telescope project and the Einstein Telescope Preparation Phase project.

Apart from her teaching, research, and management responsibilities at the university, Isabel Cordero-Carrión is highly engaged in outreach and communication. She is a member of the team behind the Oscilador Armónico podcast, a regular participant in the Coffee Break: Señal y Ruido podcast, and occasionally contributes to the A Ciencia Cierta podcast.

Luxembourg Centre for Systems Biomedicine

The Luxembourg Centre for Systems Biomedicine (LCSB) was founded in 2009 as one of the first interdisciplinary research centres of the University of Luxembourg. Our staff members combine their expertise in a broad spectrum of disciplines – from computational biology to clinical and experimental neuroscience – to study the brain and its diseases.

The LCSB aims to gain a mechanistic understanding of neurodegenerative processes and to use the resulting knowledge to develop new ways to diagnose, prevent and treat neurodegenerative disorders, like Alzheimer’s and Parkinson’s. To realise this vision, we conduct research in the field of Systems Biology and Biomedicine – in the lab, in the clinic and in silico (computer modelling and simulations).

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For over a decade, the LCSB has established a state-of-the-art infrastructure and developed skills in several fields, such as genetics, metaproteomics, enzymology and cheminformatics. We foster interdisciplinarity because we strongly believe that complex problems can only be solved when the best minds from different disciplines come together and form a team.

We work together with scientific partners worldwide and carry out collaborative projects with research-oriented companies and hospitals, to accelerate the translation of research results into clinical applications and to tackle the growing issue represented by neurodegenerative diseases worldwide.

Biomedical Research Center of the Slovak Academy of Sciences

The challenges of human health and diseases are very complex and the Biomedical Research Center of the Slovak Academy of Sciences is able to look at them from different perspectives, as it comprises five areas of biomedical research: experimental endocrinology, experimental oncology, virology, neurobiology as well as clinical and translational research. The Biomedical Research Center is a multidisciplinary institution of basic and translational research. We focus on the study of human disease mechanisms and their interactions and on the development of new preventive, screening and diagnostic approaches that are not yet available in current medical practice in Slovakia. We aim to contribute to the explanation of the causes, mechanisms and consequences of metabolic, neurobiological, neuroendocrine, autoimmune, cardiovascular, oncological and infectious diseases and to develop new strategies for combating these diseases, that represent a great health, social and economic burden on our society.

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Research projects
– experimental oncology – study of environmental, genetic, epigenetic and (patho)physiological mechanisms of carcinogenesis and cancer progression,
research and development of new approaches to cancer prevention, diagnosis and therapy.
– experimental endocrinology – research in the fields of endocrinology, neuroendocrinology and psychiatry, cardiology, exercise physiology and integrative (patho)physiology of metabolic disorders, as well as genetics and DNA diagnostics of rare disorders with focus on direct translation into the clinical practice. – – virology – research on epidemiology, pathogenesis and immunology and of viral and rickettsial infections, research and development of new diagnostic and therapeutic approaches, development of analytical methods for practice.
-neurobiology – research of central nervous system focused on vascular and traumatic disorders, mechanisms of injury, neuroprotection, and new approaches to regeneration of nerve tissue.

S. Pastorekova: Role of the CA IX ectodomain in tumor growth and metastasis
B. Smolkova: Identification of biological markers for prevention and translational medicine in pancreatic cancer
J. Ukropec: Molecular mediators of the response to complex lifestyle intervention in patients with obesity: Regulation of metabolic flexibility in vitro and in vivo
B. Ukropcova: Ameliorating Effects of Aging by Physical Exercise: Molecular, Metabolic and Structural Adaptations, Multi-Organ Integrative Approach
B. Klempa: Zoonoses Emergence across Degraded and Restored Forest Ecosystems (ZOE).

Kavli Institute for Nanoscience Discovery, University of Oxford

The Kavli Institute for Nanoscience Discovery (Kavli INsD) is a groundbreaking interdisciplinary science institute focused on world-class nanoscience research. Established in April 2021 as the 20th institute funded by the esteemed Kavli Foundation, USA, we are proud to be the University of Oxford’s first institute spanning the life, medical, and physical sciences.

Led by the distinguished Professor Dame Carol Robinson, a renowned chemist specializing in mass spectrometry and the study of protein structures, Kavli INsD is committed to making significant contributions in critical areas such as antimicrobial resistance, brain and mental health, infectious diseases, and malaria. Additionally, we strive to develop cutting-edge instrumentation that brings the analytical power of the physical sciences into the realm of cellular exploration.

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At Kavli INsD, our exceptional team of 38 faculty members and over 450 researchers represents diverse backgrounds in structural biology, biochemistry, pathology, chemistry, physics, physiology, and engineering. United by our shared focus on the nanoscale—the scale of proteins, viruses, and DNA—we are at the forefront of unravelling the mysteries of the most fundamental unit of life: the cell.
Together, we are shaping the future of nanoscience, fostering an inclusive and collaborative working culture, and driving breakthrough discoveries that have the potential to revolutionize our understanding of the world around us.
Because our institute covers two very important and highly topical subjects – research culture and interdisciplinarity we believe press coverage would be highly beneficial to publicize these messages.

Our institute also includes four current ERC Advanced, Starter and grantees (Professors Dame Carol Robinson and Molly Stevens, Professors Philipp Kukura and Andrew Baldwin. Importantly our research is also translational with both Refeyn and OMass therapeutics forming on the back of ERC Proof of concept funding.

For details please explore https://kavlinano.ox.ac.uk/research-themes.

Research Themes
1. Understanding biological function and regulation requires characterising biomolecules, and their structures and interactions. Developing new ways to study biomolecules is a major focus of our research, and the tools we develop underpin much of our work (e.g mass spectrometry, next-generation imaging, novel bioanalytic technologies, and biosensors and probes)

2. Advanced diagnostics & personalised medicine – our long-term goal is to democratise and personalise healthcare with ultrasensitive, cost-effective, user-friendly and mobile-connected diagnostic technologies.
Engineering & exploring the bio-material interface – we design biomaterials that influence the behaviour of cells at the interface of living and non-living matter by tweaking the surface chemistry and texture.
Bioelectronics & regenerative engineering – we have a growing portfolio of cutting-edge biomaterials designed to repair tissues, enhance regeneration and deliver drugs to targeted areas of the body.
Digital medicine & big data – we are harnessing the computational power of machine learning and artificial intelligence to enhance understanding of molecules, materials, and processes.

3. Infectious disease poses a huge unmet global medical need leading to ‘spillover’ events – where pathogens move from wildlife or livestock to people – become more common, increasing the frequency of pandemics. We therefore urgently need to strengthen our pandemic preparedness. We are working on SARS-CoV-2 and other coronaviruses, Dengue, Zika, Malaria, Hepatitis B & C

3. Antimicrobial resistance (AMR) is a major global health threat. In AMR, microbes such as bacteria develop the ability to survive exposure to the antibiotic drugs that are used to treat and prevent infections. Through the rise of resistance, medical procedures become riskier and common infections untreatable. It has become clear that tackling AMR requires a diverse range of actions, which include developing new antibiotics as well as rapid diagnostics that require understanding the modes of action of existing antibiotics and the mechanisms that fuel resistance, to identify new targets for novel antibiotics and to devise ways to rapidly detect the presence of drug resistance.

4. Neurodegenerative diseases and motor neuron disease, represent an increasing healthcare burden for an ageing global population. Largely untreatable, these diseases are already a leading cause of disability and their prevalence is rising. Our research aims to understand the fundamental biological processes that underlie normal brain development and are responsible for neurodegeneration, and to inform the development of treatments.

5. Amidst a persistent lack of direct evidence linking biological mechanisms to depression symptoms we are charting differences at the molecular level of receptors and transporters at the blood-brain barrier, to also develop effective biomarkers for anhedonic depression to better inform therapeutic intervention.

University of Graz – Climate Change

Understanding the climate system and climate change, exploring changing climate risks and impacts, low carbon transition solutions and building climate resilience are the major aims of one field of excellence at the University of Graz. At the Wegener Center for Climate and Global Change scientists from geophysics and climate physics, meteorology, economics, transition research, geography and regional research deal with both the physically oriented and the socio-economic aspects of climate change and global change as well as the transition to a low-carbon world.

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They are part of the network Climate Change Graz, an association of more than 100 researchers who investigate which economic, production-related, social, political and legal changes are necessary for a profound and sustainable transformation. In addition to scientific excellence the goal is to raise awareness of the urgency and personal concern, especially among opinion leaders and multipliers. And, in a further step, to initiate the creation of new framework conditions that can lead to changes in the behaviour of organisations, companies and people.
There are four research groups at the Wegener Center tackling questions such as: How is global warming developing? How are individuals and society affected by climate change? How do we achieve the net-zero target?

The University of Graz is located in the south-east of Austria. Founded in 1585, it is the second oldest and – with almost 30,000 students and nearly 5000 employees – also the second largest university of the country. It has six faculties – Humanities, Catholic Theology, Natural Sciences, Law, Social and Economic Sciences as well as Environmental, Regional and Educational Sciences. Their key objective is to conduct research at the highest level in these areas. Journalists in residence will have the opportunity to gain insights in all of them.