The challenges of human health and diseases are very complex and the Biomedical Research Center of the Slovak Academy of Sciences is able to look at them from different perspectives, as it comprises five areas of biomedical research: experimental endocrinology, experimental oncology, virology, neurobiology as well as clinical and translational research. The Biomedical Research Center is a multidisciplinary institution of basic and translational research. We focus on the study of human disease mechanisms and their interactions and on the development of new preventive, screening and diagnostic approaches that are not yet available in current medical practice in Slovakia. We aim to contribute to the explanation of the causes, mechanisms and consequences of metabolic, neurobiological, neuroendocrine, autoimmune, cardiovascular, oncological and infectious diseases and to develop new strategies for combating these diseases, that represent a great health, social and economic burden on our society.
Read More Research projects
– experimental oncology – study of environmental, genetic, epigenetic and (patho)physiological mechanisms of carcinogenesis and cancer progression,
research and development of new approaches to cancer prevention, diagnosis and therapy.
– experimental endocrinology – research in the fields of endocrinology, neuroendocrinology and psychiatry, cardiology, exercise physiology and integrative (patho)physiology of metabolic disorders, as well as genetics and DNA diagnostics of rare disorders with focus on direct translation into the clinical practice. – – virology – research on epidemiology, pathogenesis and immunology and of viral and rickettsial infections, research and development of new diagnostic and therapeutic approaches, development of analytical methods for practice.
-neurobiology – research of central nervous system focused on vascular and traumatic disorders, mechanisms of injury, neuroprotection, and new approaches to regeneration of nerve tissue.
S. Pastorekova: Role of the CA IX ectodomain in tumor growth and metastasis
B. Smolkova: Identification of biological markers for prevention and translational medicine in pancreatic cancer
J. Ukropec: Molecular mediators of the response to complex lifestyle intervention in patients with obesity: Regulation of metabolic flexibility in vitro and in vivo
B. Ukropcova: Ameliorating Effects of Aging by Physical Exercise: Molecular, Metabolic and Structural Adaptations, Multi-Organ Integrative Approach
B. Klempa: Zoonoses Emergence across Degraded and Restored Forest Ecosystems (ZOE).